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Douglas R. Flanagan, Ph.D.,
Professor,
Division of Pharmaceutics
Contact Information:
Division of Pharmaceutics, S225
College of Pharmacy
The Dale E. Wurster Center for Pharmaceutical Technology
The University of Iowa
Iowa City, IA 52242
Phone: (319) 335-8827; Fax: (319) 335-9349
Email: douglas-flanagan@uiowa.edu
Education
1967 B.S. (Pharmacy), The University of Michigan
1969 M.S. (Pharmaceutics), The University of Michigan
1971 Ph.D.. (Pharmaceutics), The University of Michigan
Professional Experience
1995 - present Professor; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
2002-2003 Head, Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1990-91 Acting Director; Division of Pharmaceutical Service, College of Pharmacy, The University of Iowa
1980-86 Head; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1978-95 Associate Professor; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1977-78 Associate Professor; School of Pharmacy, University of Connecticut
1971-77 Assistant Professor; School of Pharmacy, University of Connecticut
Research Interests
Dr. Flanagan's research interests include diffusion and dissolution phenomena, controlled release formulation, biodegradable polymeric systems, liposomal drug delivery systems and solid-state properties of drugs.
Recent Publications
Turner JW Jr, Liu IKM, Flanagan DR, Rutberg AT and Kirkpatrick JF, Immunocontraception in Feral Horses: One Inoculation Provides Two Years of Infertility, J. Wildlife Manage.71, in press (2007).
KhawamA and Flanagan DR, “Solid-State Kinetic Models: Basics and Mathematical Fundamentals,” J. Phys. Chem. B, 110, 17315-17328 (2006).
Al-Maaieh A and Flanagan DR, “Salt Effects on an Ion-Nonelectrolyte Reaction – Hydroxide Catalyzed Hydrolysis of Benzocaine” Pharm. Res., 23, 589-594 (2006).
Khawam A and Flanagan DR, “Basics and Applications of Solid-State Kinetics,” J. Pharm. Sci., 95 472-498 (2006).
Al-Maaieh A and Flanagan DR, “New Drug Salt Formation in Biodegradable Microspheres,” Int. J. Pharm., 303, 153-159 (2005).
Grieg NH, Ruckle J, Comer P, Brownell L, Holloway HW, Flanagan DR, Canfield CJ and Burford RG, “Anticholinesterase and Pharmacokinetic Profile of Phenserine in Healthy Elderly Human Subjects,” Curr. Alzheimer Res. 2, 483-492 (2005).
Khawam A and Flanagan DR, “Role of Isoconversional Methods in Varying Activation Energies of Solid-State II. Nonisothermal Kinetic Studies,” Thermochim. Acta, 436, 101-112 (2005).
Liu IKM, Turner JW Jr, VanLeeuwen EMG, Flanagan DR, Hedrick JL, Murata K, Lane VM and Morales-Levy MP, Persistence of Anti-Zona Pellucidae Antibodies Following a Single Innoculation of Porcine Zona Pellucidae in the Domestic Equine, Reproduction, 129, 181-190 (2005).
Khawam A and Flanagan DR, Role of Isoconversional Methods in Varying Activation Energies of Solid-State Kinetics I. Isothermal Kinetic Studies, Thermochim. Acta, 429, 93-102 (2005).
Khawam A and Flanagan DR, Complementary Use of Model-Free and Modelistic Methods in the Analysis of Solid-State Kinetics, J. Phys. Chem. A, 109, 10073-10080 (2005).
Oh YK and Flanagan DR, "Swelling and Permeability Characteristics of Zein Membranes," PDA J. Pharm. Sci. Tech., 57, 208-217 (2003).
Kumar N, Krishnan M, Azzam T, Magora A, Ravikumar MNV, Flanagan DR and Domb AJ, "Analysis of Fatty Acid Anhydrides and Polyanhydrides," Anal. Chim. Acta, 465, 257-272 (2002).
Wang J and Flanagan DR, "General Solution for Diffusion-Controlled Dissolution of Spherical Particles. 2. Evaluation of Experimental Data," J. Pharm. Sci., 91, 534-542 (2002).
Al-Maaieh A and Flanagan DR, "Salt Effects on Caffeine Solubility, Distribution and Self-Association" J. Pharm. Sci,. 91, 1000-1008 (2002).
Turner JW Jr, Liu IKM, Flanagan DR, Bynum KS and Rutberg AT, "Porcine Zona Pellucida (PZP) Immunocontraception of Wild Horses (Equus Caballus) in Nevada: a 10 Year Study, Reproduction (Supplement 60, Fifth International Symposium on Fertility Control of Wildlife), 177-186 (2002).
Kavita K, Donovan MD and Flanagan DR, "Drug Transfer through Mucus," Adv. Drug Deliv. Rev., 48, 173-193 (2001)
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