| Friday, April 25, 2008 |
| 3:00 – 6:30 pm |
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Conference Registration
Sheraton Hotel (Map location 1) |
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Conference Oral Presenters: Check-in with Garrett Rettig |
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| 6:30 – 10:00 pm |
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Welcome Reception/Dinner
Kinnick Stadium Press Box (Map location 2)
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| Saturday, April 26, 2008 |
| 7:00 – 8:30 am |
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Continental Breakfast
John Pappajohn Business Building, Andersen Galleria (Map location 3) |
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All Saturday Oral Presenters (Sessions I and II): Check-in with Garrett Rettig
W10 John Pappajohn Business Building |
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Poster Set-up
Hotel Vetro - Ballroom |
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| 9:00 am |
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Opening Remarks and Welcome |
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Dr. Jordan Cohen, Interim Vice President for Research, Emeritus Professor and Dean, The University of Iowa |
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Dr. John Keller, Dean, Graduate College, The University of Iowa |
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| Session I |
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Jennifer Rees, Presiding
W10 John Pappajohn Business Building |
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| 9:15 – 9:35 am |
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Studies on the Kinetic Mechanism of Human Hydroxysteroid Sulfotransferase hSULT2A1
Hayrettin Ozan Gulcan and Michael W. Duffel
The University of Iowa |
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| 9:35 – 9:55 am |
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DNA Adduct Formation in Extra-hepatic Tissues of F344 Rats Chronically Treated with Tobacco-specific Nitrosamines
Siyi Zhang, Peter W. Villalta, Mingyao Wang, Shannon L. Nord, and Stephen S. Hecht
The University of Minnesota |
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| 9:55 – 10:15 am |
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Novobiocin Analogues that Possess Potent Anti-tumor Activity
Alison C. Donnelly and Brian S. J. Blagg
The University of Kansas |
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| 10:15 – 10:35 am |
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From Serendipity to Rational Antituberculosis Drug Discovery on Mefloquine-based Ligands
Jialin Mao, Hai Yuan, Annamaria Lilienkampf, Yang Song, Richard B. van Breemen, Alan P.Kozikowski, andScott G. Franzblau
The University of Illinois at Chicago |
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| 10:35 am |
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Break (coffee and pastries provided) |
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| Keynote Lecture |
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Beth Miskimins Mills, Presiding
W10 John Papajohn Business Building |
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| 11:00 – 12:00 pm |
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Molecular Machines That Assemble Biological Membranes
Dr. Daniel Kahne
Departments of Chemistry and Chemical Biology, Harvard University |
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| 12:00 – 12:30 pm |
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Break and Poster Set-up |
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| 12:30-3:00 pm |
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Lunch and Poster Presentation
Hotel Vetro, E.W. Lehman Ballroom (Map location 4) |
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| Session II |
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David Anderson, Presiding
W10 John Papajohn Business Building |
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| 3:30 – 3:50 pm |
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LC-MS/MS Quantification of PGE2 and PGD2 in Biological Fluids
Hongmei Cao, Lei Xiao, Gye Young Park, Xuerong Wang, Anser Azim, John W. Christman, Richard B. van Breemen
The University of Illinois at Chicago |
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| 3:50 – 4:10 pm |
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A Journey in Biocatalysis and Organic Synthesis
Antonio Osorio-Lozada and Horacio F. Olivo
The University of Iowa |
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| 4:10 – 4:30 pm |
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Human Cytochrome P450 2E1: Functional Comparisons to Cytochromes P450 2A13 and 2A6
Melanie Blevins and Emily Scott
The University of Kansas |
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| 4:30 – 4:50 pm |
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Toward the Design and Modeling of Protein-protein Interactions in a Chemically Induced Dihydrofolate Reductase Dimer
Brian R. White, Elizabeth A. Amin, Carston R. Wagner, and Donald G. Truhlar
The University of Minnesota |
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| 6:00-7:00 pm |
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Cocktail hour and hors d’oeuvres
Sheraton Hotel, Amos Dean Ballroom |
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| 7:00-10:00 pm |
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Banquet Dinner |
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Sunday, April 27, 2008 |
| Check Out |
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Sheraton Hotel |
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| 7:00 – 9:00 am |
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Continental Breakfast
John Pappajohn Business Building, Andersen Galleria |
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All Sunday Oral Presenters (Sessions III and IV): Check-in with Garrett Rettig
W10 John Pappajohn Business Building |
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| Session III |
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Garrett Rettig, Presiding
W10 John Pappajohn Business Building |
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| 9:00 – 9:20 am |
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Investigation of Phenol Sulfotransferase Inhibition Through Interactions with Carboxylic Acids
Jason T. Smart and Michael W. Duffel
The University of Iowa |
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| 9:20 – 9:40 am |
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Synthesis and Structure-Activity Relationships of Tubulysins
sRanganathan Balasubramanian and Robert A. Fecik
The University of Minnesota |
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| 9:40 – 10:00 am |
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A Short Total Synthesis of (+)-Antofine
Micah Niphakis and Gunda I. Georg
The University of Kansas |
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| 10:00 – 10:20 am |
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Comparative Analysis of Flurbiprofen and NO-flurbiprofen Activity in Models of Inflammation, Neurodegeneration and Memory Impairment
Samer Abdul-Hay, Min Li, Rezene T Asghodom, Praneeth D Edirisinghe, and Gregory Thatcher
The University of Illinois at Chicago |
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| 10:20 – 10:50 am |
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Break (coffee and pastries provided) |
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| Session IV |
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Amanda Fenner, Presiding
W10 John Papajohn Business Building |
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| 10:50 – 11:10 am |
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Inactivation of Intracellular Arylamine N-Acetyltransferase 1 (NAT1) by Nitrosoarenes
Li Liu, Carston R. Wagner, and Patrick E. Hanna
The University of Minnesota |
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| 11:10 – 11:30 am |
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Synthesis of High Mannose N-Glycan Bioconjugates as Targeted Gene Delivery Ligands
Kevin Anderson and Kevin G. Rice
The University of Iowa
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| 11:30 – 11:50 am |
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Structure-Activity Relationships in TLR-2 Agonistic Lipopeptides
Wenyan Wu, Rongti Li, Apurba Dutta and Sunil A. David
The University of Kansas |
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| 11:50 – 12:10 am |
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In vitro Serotonergic Activity of Black Cohosh (Cimicifuga racemosa) and Identification of its Active Constituent N-methylserotonin
Sharla L. Powell, Tanja Goedecke, Shao-Nong Chen, Dejan Nikolic, Birgit Dietz, Norman R. Farnsworth, Richard van Breeman, Guido F. Pauli, and Judy L. Bolton
The University of Illinois at Chicago
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| 12:15 pm |
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Closing of the 46th MIKI Meeting
Beth Miskimins Mills |
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| 12:20 pm |
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Adjournment and Faculty Meeting |
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Pick-up Boxed Lunches
John Pappajohn Business Building, Andersen Galleria |
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