Advanced Problem Solving in Pharmacological Sciences |
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Course Offering: Fall and Spring Annually
Course Co-Coordinators: Associate Professor Dawn Quelle and Professor Kevin
Rice
Credits: 1 credit
Grading: S/U
This is a required
course for all students supported on the Pharmacological Sciences
Training Grant. The primary goal of this course is to expose
students to a broad range of scientific expertise and experimental
designs, to develop interpersonal problem solving skills, and
to propose plans of study for solving contemporary scientific
problems in the Pharmacological Sciences.
The course will
meet once a month on the first Thursday of the month in 2-322 BSB from 4:30 - 6:00pm. The faculty
host will provide a one hour presentation to the students and
provide an appropriate handout. The subject of each presentation
will involve some methodology, strategy, or approach commonly
used to solve problems in the pharmacological sciences. The
format will include examples of how the method, strategy or
approach has been successfully used to derive scientific information
and to advance knowledge in the pharmacological sciences. The
faculty host will provide students with one significant unsolved
problem to serve as the format for a group thought experiment
to be completed independently.
The students will
be required to meet at least three times per month outside of
class to discuss possible solutions to the problem posed to
them. The students must work collaboratively to bring together
their combined expertise and background to shape a "Plan
of Study" (described below) that will be submitted to the
faculty host in response to the problem posed. The students
should not feel limited to using methodology or strategies that
were presented in that session, but should look at this as a
cumulative exercise that may include any and all methods, strategies
and approaches to propose solutions to the problem. A selected
student correspondent will be responsible for organizing the
outside class discussions and to prepare and submit the Plan
of Study. The faculty host will critique the Plan of Study and
provide written feedback to the group.
One of the primary
goals of this class is to bring together interdisciplinary scientists
to work together to design a collaborative plan of study, to
communicate and share ideas, and to propose workable solutions
to contemporary problems in the Pharmacological Sciences. Students
supported on the training grant must select this course for
4 semesters, resulting in exposure to 14 faculty and numerous
peers in the Pharmacological Sciences. |
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Composition of the Plan of Study
The report should be prepared in Word to be e-mailed to the faculty host, three weeks following the presentation. The report should be paged numbered and be between five and ten pages double space, including embedded figures. The following subheadings should be used.
1. Title
2. Summary of the Problem, restate the problem in one-half page.
3. Experimental Design, write a detailed experimental plan of study, reference the source of any reagents (either commercial or donated), tissues, organisms or biological material that you will use in your study. Your plan of study must contain the following:
Plan A: description of experimental design and control experiments.
Plan B: description of experimental design and control experiments.
Plan C: description of experimental design and control experiments.
4. Anticipated Results from Plan A, B and C, drawings, diagrams, graphs, chromatograms, gels or numerical data illustrating the desired outcome of plan A-C (this section may be integrated in plan A-C above).
5. Potential Pitfalls, point out what your group felt is the weakest or riskiest part of the plan.
6. Timeline: provide a timetable to achieve each part of the Plan of Study,
7. References: provide a citation list of reference used throughout sections 2-4.
8. Participation: indicate the relative contribution of each member of the team.
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Schedule
of Presentations |
Date |
Presentation |
Faculty |
Student
Correspondent |
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| Fall 2008 |
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09/04/08 |
Welcome and Overview of the course
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Profs. Dawn Quelle and Kevin Rice |
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10/02/08 |
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Prof. Shahram Khademi |
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Student Plan of Study |
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Faculty Evaluation |
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11/06/08 |
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Prof.
Donna Hammond |
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Student Plan of Study |
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Faculty Evaluation |
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12/11/08 |
"Discovery and Synthesis of Naturally Occurring Peptides with Potent Biological Activity"
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Prof.
Greg Friestad |
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Student Plan of Study |
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Faculty Evaluation |
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| Spring 2008 |
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2/7/08 |
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Prof. Mark Anderson |
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Student Plan of Study |
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3/6/08 |
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Prof. Jon Doorn |
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Student Plan of Study |
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Faculty Evaluation |
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4/3/08 |
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Prof. Mary Horne |
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Student Plan of Study |
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Faculty Evaluation |
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| Fall 2007 |
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09/06/07 |
Course Overview and Discussion on "How to Write a Strong Proposal"
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Profs. Dawn Quelle and Kevin Rice |
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10/04/07 |
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Prof. Yuriy Usachev |
Jacqueline Smits
(Chemistry) |
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Student Plan of Study |
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11/01/07 |
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Prof.
Ernesto Fuentes |
Patrick Houlihan (Pharmacology) |
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12/06/07 |
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Prof.
Robert Kerns |
Julie He
(Physiology) |
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Student Plan of Study |
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Faculty Evaluation |
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| Spring 2007 |
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02/01/07 |
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Prof.
Raymond Hohl |
Anderson, Buffington,
Dallapiazza, Dudakovic, Houlihan, Johnson, Lozama, Mente,
Pena-Silva, Smith |
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Faculty Evaluation |
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03/01/07 |
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Prof.
Mike Duffel |
Anderson, Buffington,
Dallapiazza, Dudakovic, Houlihan, Johnson, Lozama, Mente,
Pena-Silva, Smith |
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04/05/07 |
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Prof.
Dawn Quelle |
K. Anderson,
M. Buffington,
R. Dallapiazza, A. Dudakovic,
P. Houlihan, A. Johnson,
R. Pena-Silva, T. Smith,
A. Lozama,
N. Mente
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| Fall 2006 |
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09/07/06 |
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Prof.
Rick Domann |
Kevin Anderson (MNPC)
Amy Halt (Pharmacology) |
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Faculty Evaluation |
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10/05/06 |
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Prof.
Don Heistad |
Ricardo Pena Silva (Pharmacology)
Robert Dallapiazza (Pharmacology)
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Faculty Evaluation |
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11/02/06 |
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Prof.
David Sheff |
Kevin Anderson (MNPC)
Jason Ulrich (Pharmacology) |
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Faculty Evaluation |
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12/07/06 |
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Prof. Scott Moye-Rowley |
Kevin Anderson (MNPC)
Jason Ulrich (Pharmacology)
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Faculty Evaluation |
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Spring 2006 |
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02/02/06 |
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Prof. Amnon Kohen |
Amy Halt (Pharmacology) |
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03/02/06 |
The Dos and Don'ts of Structure Assisted Ligand Design |
Prof. S. Ramaswamy |
Kevin Tidgewell (MNPC) |
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Student Plan of Study |
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Faculty Evaluation |
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04/06/06 |
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Prof. Stefan Strack |
Garrett Rettig (MNPC) |
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Student Plan of Study |
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Faculty Evaluation |
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| Fall 2005 |
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09/01/05 |
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Prof. Michael Henry |
Garrett Rettig (MNPC) |
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10/06/05 |
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Prof. Andy Russo |
Kevin Anderson (MNPC) |
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11/03/05 |
Strategies to Develop Drugs for Stroke Treatment |
Prof. Johannes Hell |
Nolan Mente (Chemistry) |
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Student Plan of Study |
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Faculty Evaluation |
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12/01/05 |
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Prof. Dave Wiemer |
Justin Drake (Physiology) |
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Spring 2005 |
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02/03/05 |
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Prof. Kevin Rice |
Amy Halt (Pharmacology) |
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Student Plan of Study |
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03/03/05 |
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Prof. Jerry Gebhart |
Kevin Tidgewell (MNPC) |
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Student Plan of Study |
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04/07/05 |
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Prof. Tom Prisinzano |
Arianne Waseen (Pharmacology) |
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