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Advanced Problem Solving in Pharmacological Sciences

Newsletter
    March 06
    June 06

Advanced Problem Solving in Pharmacological Sciences
 

Course Offering: Fall and Spring Annually

Course Co-Coordinators: Associate Professor Dawn Quelle and Professor Kevin Rice

Credits: 1 credit

Grading: S/U

This is a required course for all students supported on the Pharmacological Sciences Training Grant. The primary goal of this course is to expose students to a broad range of scientific expertise and experimental designs, to develop interpersonal problem solving skills, and to propose plans of study for solving contemporary scientific problems in the Pharmacological Sciences.

The course will meet once a month on the first Thursday of the month in 2-322 BSB from 4:30 - 6:00pm. The faculty host will provide a one hour presentation to the students and provide an appropriate handout. The subject of each presentation will involve some methodology, strategy, or approach commonly used to solve problems in the pharmacological sciences. The format will include examples of how the method, strategy or approach has been successfully used to derive scientific information and to advance knowledge in the pharmacological sciences. The faculty host will provide students with one significant unsolved problem to serve as the format for a group thought experiment to be completed independently.

The students will be required to meet at least three times per month outside of class to discuss possible solutions to the problem posed to them. The students must work collaboratively to bring together their combined expertise and background to shape a "Plan of Study" (described below) that will be submitted to the faculty host in response to the problem posed. The students should not feel limited to using methodology or strategies that were presented in that session, but should look at this as a cumulative exercise that may include any and all methods, strategies and approaches to propose solutions to the problem. A selected student correspondent will be responsible for organizing the outside class discussions and to prepare and submit the Plan of Study. The faculty host will critique the Plan of Study and provide written feedback to the group.

One of the primary goals of this class is to bring together interdisciplinary scientists to work together to design a collaborative plan of study, to communicate and share ideas, and to propose workable solutions to contemporary problems in the Pharmacological Sciences. Students supported on the training grant must select this course for 4 semesters, resulting in exposure to 14 faculty and numerous peers in the Pharmacological Sciences.

 

Composition of the Plan of Study

 

The report should be prepared in Word to be e-mailed to the faculty host, three weeks following the presentation. The report should be paged numbered and be between five and ten pages double space, including embedded figures. The following subheadings should be used.

 

1. Title

2. Summary of the Problem, restate the problem in one-half page.
3. Experimental Design, write a detailed experimental plan of study, reference the source of any reagents (either commercial     or donated), tissues, organisms or biological material that you will use in your study. Your plan of study must contain the     following:

                  Plan A: description of experimental design and control experiments.

                  Plan B: description of experimental design and control experiments.

                  Plan C: description of experimental design and control experiments.

4. Anticipated Results from Plan A, B and C, drawings, diagrams, graphs, chromatograms, gels or numerical data     illustrating the desired outcome of plan A-C (this section may be integrated in plan A-C above).

5. Potential Pitfalls, point out what your group felt is the weakest or riskiest part of the plan.

6. Timeline: provide a timetable to achieve each part of the Plan of Study,

7. References: provide a citation list of reference used throughout sections 2-4.

8. Participation: indicate the relative contribution of each member of the team.

Schedule of Presentations
Date
Presentation
Faculty
Student Correspondent
 
Fall 2008  
09/04/08

Welcome and Overview of the course

Profs. Dawn Quelle and Kevin Rice
 
10/02/08
Prof. Shahram Khademi
 
 
Student Plan of Study
 
Faculty Evaluation
 
11/06/08
Prof. Donna Hammond
 
Student Plan of Study
 
Faculty Evaluation
 
12/11/08
"Discovery and Synthesis of Naturally Occurring Peptides with Potent Biological Activity"
Prof. Greg Friestad
 
Student Plan of Study
 
Faculty Evaluation
 
         
Spring 2008  
2/7/08
Prof. Mark Anderson
 
Student Plan of Study
 
 
3/6/08
Prof. Jon Doorn
 
Student Plan of Study
 
Faculty Evaluation
 
4/3/08

Analysis of Cell Cycle by Flow Cytometry
Paper 1           Paper 2
Paper 3           Paper 4

Prof. Mary Horne
 
Student Plan of Study
 
Faculty Evaluation
 
         
Fall 2007  
09/06/07

Course Overview and Discussion on "How to Write a Strong Proposal"

Profs. Dawn Quelle and Kevin Rice
 
10/04/07
Prof. Yuriy Usachev
Jacqueline Smits
(Chemistry)
 
Student Plan of Study
 
 
11/01/07
Prof. Ernesto Fuentes
Patrick Houlihan (Pharmacology)
 
 
 
12/06/07
Prof. Robert Kerns
Julie He
(Physiology)
 
Student Plan of Study
 
Faculty Evaluation
 
         
Spring 2007  
02/01/07
Prof. Raymond Hohl
Anderson, Buffington,
Dallapiazza, Dudakovic, Houlihan, Johnson, Lozama, Mente,
Pena-Silva, Smith
 
 
Faculty Evaluation
 
03/01/07
Prof. Mike Duffel
Anderson, Buffington,
Dallapiazza, Dudakovic, Houlihan, Johnson, Lozama, Mente,
Pena-Silva, Smith
 
 
 
04/05/07
Prof. Dawn Quelle
K. Anderson, M. Buffington,
R. Dallapiazza, A. Dudakovic,
P. Houlihan, A. Johnson,
R. Pena-Silva, T. Smith,
A. Lozama, N. Mente
 
 
 
         
Fall 2006  
09/07/06
Prof. Rick Domann
Kevin Anderson (MNPC)
Amy Halt (Pharmacology)
 
 
 
Faculty Evaluation
 
10/05/06
Prof. Don Heistad

Ricardo Pena Silva (Pharmacology)
Robert Dallapiazza (Pharmacology)

 
 
 
Faculty Evaluation
 
11/02/06
Prof. David Sheff
Kevin Anderson (MNPC)
Jason Ulrich (Pharmacology)
 
 
Faculty Evaluation
 
12/07/06
Prof. Scott Moye-Rowley
Kevin Anderson (MNPC)
Jason Ulrich (Pharmacology)
 
Faculty Evaluation
 
         
Spring 2006
 
02/02/06
Prof. Amnon Kohen
Amy Halt (Pharmacology)
 
 
 
   
 
03/02/06
The Dos and Don'ts of Structure Assisted Ligand Design
Prof. S. Ramaswamy
Kevin Tidgewell (MNPC)
 
Student Plan of Study
Faculty Evaluation
04/06/06
Prof. Stefan Strack
Garrett Rettig (MNPC)
Student Plan of Study
Faculty Evaluation
 
         
Fall 2005  
09/01/05
Prof. Michael Henry
Garrett Rettig (MNPC)
 
 
 
10/06/05
Prof. Andy Russo
Kevin Anderson (MNPC)
 
 
 
11/03/05
Strategies to Develop Drugs for Stroke Treatment
Prof. Johannes Hell
Nolan Mente (Chemistry)
 
Student Plan of Study
 
Faculty Evaluation
 
12/01/05
Prof. Dave Wiemer
Justin Drake (Physiology)
 
 
 
         
Spring 2005
 
02/03/05
Prof. Kevin Rice
Amy Halt (Pharmacology)
 
Student Plan of Study
 
 
03/03/05
Prof. Jerry Gebhart
Kevin Tidgewell (MNPC)
 
Student Plan of Study
 
 
04/07/05
Prof. Tom Prisinzano
Arianne Waseen (Pharmacology)
 
 
 
 
         
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supported by the National Institute of General Medical Sciences.
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