Blazer LL, Roman DL, Muxlow MR, and Neubig RR. Use of flow cytometric methods to quantify protein-protein interactions. Current protocols in cytometry [1934-9297] Blazer, 2010 Chapter 13 pp. 13.11.1 - 13.11.15
Roman, DL. Identification of Ligands Targeting RGS Proteins: High-Throughput Screening and Therapeutic Potential. In Rory A. Fisher, editor: Progress in Molecular Biology and Translational Science, Vol. 86, Burlington: Academic Press, 2009, pp. 335-356.
Roof RA, Roman DL, Clements ST, Sobczyk-Kojiro K, Blazer LL, Ota S, Mosberg HI, Neubig RR.
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen. BMC Pharmacol. 2009, 9:(9).
Roman DL, Ota S and Neubig RR. Polyplexed flow cytometry protein interaction assay: a novel high-throughput screening paradigm for RGS protein inhibitors. J Biomol Screen. 2009, 14(6):610-619.
Talbot JN, Roman DL, Clark MJ, Roof RA, Tesmer JJ, Neubig RR and Traynor JR. Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent. Journal of Neurochemistry. 2009, In Press.
Pei J, Dishinger JF, Roman DL, Rungwanitcha C, Neubig RR, Kennedy RT. Microfabricated channel array electrophoresis for characterization and screening
of enzymes using RGS-G protein interactions as a model system.
Anal Chem. 2008 Jul 1;80(13):5225-31.
Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR,
Kozasa T, and Tesmer JJ. Assembly of High Order G alpha q-Effector Complexes with
RGS Proteins.
J Biol Chem. 2008 Dec 12;283(50):34923-34.
Roof RA, Sobczyk-Kojiro K, Turbiak AJ, Roman DL, Pogozheva ID, Blazer LL,
Neubig RR, Mosberg HI. Novel Peptide Ligands of RGS4 from a Focused One-Bead, OnCompound Library. Chem Biol Drug Des. 2008 Jul 14.
Bernsteel DJ, Roman DL and Neubig RR. In vitro protein kinase activity measurement by flow cytometry. Analytical Biochemistry,
Anal Biochem. 2008 Dec 15;383(2):180-5.
Roman DL, Talbot JN, Roof RA, Sunahara RK, Traynor JR & Neubig RR. Identification of small molecule inhibitors of Regulator of G-protein Signaling 4 (RGS4) using a high throughput flow cytometry protein interaction assay (FCPIA). Mol Pharmacol. 2007, 71,1 169-175
Roof RA, Jin Y, Roman DL, Sunahara RK, Ishii M, Mosberg HI & Neubig RR. Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins. Chemical Biology & Drug Design, 2006, 67, 266-274.
Roman DL, Walline CC, Rodriguez GJ, Barker EL. Interactions of antidepressants with the serotonin transporter: a contemporary molecular analysis.
Eur J Pharmacol. 2003 Oct 31;479(1-3):53-63.
Roman DL, Saldana SN, Nichols DE, Carroll FI & Barker EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics, 2004, 308, 679-687. |
