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Pharmaceutical Sciences
MIKI 2008

Charles Barfknecht

Education
  • B.S., Pharmacy (honors), University of Wisconsin, Madison, 1960
  • Ph.D., Medicinal Chemistry, University of Kansas, 1964
  • Graduate studies done with Professor Edward E. Smissman with a National Institutes of Health pre doctoral fellowship.
Professional Experience
Idaho State University, Assistant Professor, 1964-1967
University of Iowa, College of Pharmacy, Assistant Professor, 1967-1969
University of Iowa, College of Pharmacy, Associate Professor, 1969-1974
 University of Iowa, College of Pharmacy Professor, 1974-
Research
Dr. Barfknecht's current research interests center on glaucoma drugs, agents for the treatment of dry eye, and sigma ligands.
Representative Publications
Schoenwald, R. D.; Vidvauns, S.; Wurster, D. E.; Barfknecht, C. F., Tear film stability of protein extracts from dry eye patients administered a sigma agonist, J. Ocular Pharmacol. 1997, 13, 151.
Schoenwald, R. D.; Vidvauns, S.; Wurster, D. E.; Barfknecht, C. F., The influence of the proteins on tear film stability in the rabbit, J. Ocular Pharmacol. Ther. 1998, 14, 15-29.
Schoenwald, R.D.; Yang, Y.S.; Xia, E.; Barfknecht, C.F., Uptake of N, N-dimethyl-2-phenylethylamine HC1 into Acini Cells Removed fromRabbit Lacrimal Glands, J. Ocular Pharmacol. Ther. 1998, 14, 253-262
Schoenwald, R.D.; Tandon, V.; Wurster, D.E.; Barfknecht, C.F. Significance of melanin binding and metabolism in the activity of 5-acetoxyacetylimino-4-methyl-delta 2-1, 3, 4- thiadiazolin-2-sulfonamide, Eur. J. Pharmaceutics Biopharm. 1998, 46, 39-50.
Representative Patents
Schoenwald, R.D. & Barfknecht, C.F., Ocular Protein Stimulants, U.S. Pat. 5,961,987 October 5, 1999.
Schoenwald, R.D. & Barfknecht, C.F., Lacrimal Secretion Stimulant (LSS), Japanese Patent #, April 28, 1999.
Schoenwald, R.D. & Barfkencht, C.F., Tetrahydroquinoline Analogues for Use n Glaucoma Treatment, U.S. Pat. 4,776, 482 July 7, 1998.
Schoenwald, R. D.; Barfknecht, C. F., Topical Use of Ethyl Ethacrynate for Glaucoma Treatment, U. S. Patent 5,654,335 August 5,1997.

College of Pharmacy
115 S. Grand Avenue Iowa City,
Iowa 52240
(319) 335-8794

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