| EDUCATION |
|
Doctor of
Philosophy, Pharmaceutics, University of Iowa, 1992. |
|
Master of
Science, Hospital/Clinical Pharmacy, University of Iowa,
1978. |
|
Bachelor
of Science, Pharmacy, University of Iowa, 1976. |
| Professional
Experience |
|
Associate Professor (Clinical),
University of
Iowa
College
of Pharmacy, 2004-Present.
|
|
Director,
Iowa
Drug Information Network,
|
|
Assistant Professor (Clinical),
University of
Iowa
College
of Pharmacy, 2001-2004. |
|
Assistant Professor,
University
of
Iowa
College
of Pharmacy, 1994-2001. |
|
Clinical Pharmacist,
University
of
Iowa
Hospitals & Clinics, 1992-1994. |
|
Adjunct Clinical Faculty,
University
of
Iowa
College
of Pharmacy,
1990-1991. |
|
Part-time Pharmacist, Veteran’s
Administration Hospital Pharmacy, 1985-1992. |
|
Teaching Assistant,
University
of
Iowa
College
of Pharmacy,
1985-1989. |
|
Consulting Pharmacist,
Dept.
Health & Social
Welfare
,
South Africa,
1979-1984. |
| Honors and Awards
|
|
Certificate
of Appreciation for Generous Service, AAPS Visiting
Scientist Program, 2005. |
|
Chair
Bioinformatics Panel of the Annals of Pharmacotherapy
Editorial Board, 2003. |
|
Dr. Warren
E. Weaver Service Award for service to others, 2000. |
|
New
Investigator Award, Am. Assoc. of Colleges of Pharmacy, 1996. |
|
The
Abbott Laboratories Teaching Assistant Fellowship, 1986-1987. |
|
Membership
Rho Chi Society, the Pharmacy Honor Society, 1978. |
|
| Select Scholarly
Activities |
|
Herman RA, Kee VR, Moores KG and Ross MB: What factors influence the occurrence of community-associated MRSA and how is it best treated? Am J Health Syst Pharm 2007; |
|
Herman RA: Role of Drug Therapy in Mild Cognitive Impairment (0.1 CEU). World Drug Info 2007;18(3):1-5. |
|
Herman RA: Book Review: Basic Pharmacokinetics. J Pharm Technol 2007;23 (?):? |
|
Herman RA: PDA's to enhance pharmaceutical care at the point of care. Pharmacy ME 2007;15(2):18-20. |
|
Herman RA: Book Review: MEDLINE: A Guide to Effective Searching in PubMed and Other Interfaces, 2nd Edition. Ann Pharmacother 2006;40(10):1894-1895. |
|
Herman RA: New Publications: Mosby's Drug Consult 2005 Handheld Software on CD-ROM (Mosby's Rx). J Pharm Technol 2006;22(2):132-133 |
|
Herman RA: Drug Information, PDAs and Primary Literature: What's the Connection? World Drug Info 2006;17(1):1-7 |
|
Goedken AM and Herman RA: Once-daily abacavir in place of twice-daily administration. Ann Pharmacother 2005;39(7-8):1302-1308. PubMed ID: 15956231 IDIS/Web ID: 535383 |
|
Modrzejewski KA and Herman RA: Emtricitabine: a once-daily nucleoside reverse transcriptase inhibitor. Ann Pharmacother 2004;38(6):1006-1014. PubMed ID: 15121999 IDIS/Web ID: 538505 |
|
Herman RA: Safe administration of intravenous immune globulin (IVIG). (0.1 CEU). World Drug Info 2004;15(1):1-5. IDIS/Web ID: 526055 |
|
Herman RA, Noormohamed S, Hirankarn
S, Shelton MJ, Huang E, Morse GD, Hewitt RG and Stapleton
JT: Comparison of a neural network approach with five
traditional methods for predicting creatinine clearance
in patients with human immunodeficiency virus infection.
Pharmacotherapy 1999;19(6):734-740. PubMed ID: 10391419 |
|
Herman RA, Veng-Pedersen
P, Miotto J, Komorowski J and Kealey GP: Pharmacokinetics
of morphine sulfate in patients with burns. J Burn
Care Rehabil 1994;15(2):95-103. PubMed ID: 8195267 |
|
Herman RA and Veng-Pedersen P: Quantitative
structure-pharmacokinetic relationships for systemic
drug distribution kinetics not confined to a congeneric
series. J Pharm Sci 1994;83(3):423-428. PubMed ID:
8207695 |
|
Furst DE, Herman RA,
Koehnke R, Ericksen N, Hash L, Riggs CE, Porras A and
Veng-Pedersen P: Effect of aspirin and sulindac on
methotrexate clearance. J Pharm Sci 1990;79(9):782-786.
PubMed ID: 2273459 IDIS/Web ID: 271200 |
|
Herman RA, Veng-Pedersen P, Hoffman
J, Koehnke R and Furst DE: Pharmacokinetics of low-dose
methotrexate in rheumatoid arthritis patients. J Pharm
Sci 1989;78(2):165-171. PubMed ID: 2715941 IDIS/Web
ID: 250620 |
|
Rooney TW, Lorber
A, Veng-Pedersen P, Herman RA, Meehan R, Hade J, Hade
A and Furst DE: Gold pharmacokinetics in breast milk
and serum of a lactating woman. J Rheumatol 1987;14(6):1120-1122.
PubMed ID: 3125315 |
|
Helling DK, Hepler CD and Herman RA:
Comparison of computer-assisted medical record audit
with other drug use review methods. Am J Hosp Pharm
1979;36(12):1665-1671. PubMed ID: 525643 |
|
| Research interests |
|
During my doctoral program I was involved
in a number of projects where I learned skills necessary
to use a two stage approach to descriptive pharmacokinetics. I
looked at the pharmacokinetics of gold in breast milk,
the pharmacokinetics of low-dose methotrexate and at
an interaction between methotrexate, sulindac and aspirin. Then
utilizing structure activity relationships I used a
traditional statistical approach to predict pharmacokinetics
of various drugs from their physicochemical characteristics. Towards
the end of the training I learned to use a neural network
for its ability to identify patterns and make predictions.
During my service in the Burn Treatment Center I had
numerous opportunities to investigate altered pharmacokinetics
in the hypermetabolic burn population. Collaborations
with other faculty members has allowed me to assist in
the pharmacokinetic analysis of other problems with cyclosporin
in transplant patients and creatinine clearance in HIV
patients. I developed these research collaborations
as a result of the pharmacokinetic/pharmacodynamic computational
lab that I operated at that time.
My research focus was in evaluating various computational
tools to forecast pharmacokinetic or pharmacodynamic
responses. My initial work was using a traditional
two stage approach where I used a linear systems (model-independent)
approach to summarize each subject’s pharmacokinetics
and then used statistics to summarize the population. Then,
I began to focus on neural networks which can identify
various patterns and make predictions based on those
recognitions. I have completed a number of projects
to demonstrate the usefulness of this tool. I have
recently started to compare this technique to other techniques;
Bayesian forecasting, mixed effect modeling (NonMEM®)
along with the traditional two stage pharmacokinetic
approach.
Now my research activities have begun to focus on utilizing
technology to facilitate the delivery of pharmaceutical
care. I have recently developed some software for
PDA’s that can be used for clinical pharmacokinetic
dosing at the bedside. I am currently looking into the
development of PDA tools that will facilitate the collection
and delivery of drug information. |
|
Ronald
A Herman , Ph.D. 